| Phenotype: | caudal vein plexus endothelial cell proliferation disrupted, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | caudal vein plexus |
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| Synonyms: | |
| Definition: | Post-vent vasculature which forms an interconnecting network of venous tubes. The caudal vein plexus forms via a very active period of angiogenic sprouting, beginning at 25 hpf when venous endothelial cells of the posterior cardinal vein sprout and migrate ventrally, then fuse with neighboring tip cells. This process reiterates during a five-hour window, forming a primordial plexus by 30 hpf. By two days of development, the primitive caudal vein plexus has matured into a complex, well-perfused, venous vascular network. Starting at 4 dpf the caudal vein plexus starts to remodel and simplify. |
| Ontology: | Anatomy Ontology [ZFA:0001286] |
| Name: | endothelial cell proliferation |
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| Synonyms: | |
| Definition: | The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium. |
| Ontology: | GO: Biological Process [GO:0001935] QuickGO AmiGO |
| Name: | disrupted |
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| Synonyms: | |
| Definition: | A quality of a single process inhering in a bearer by virtue of the bearer's being interrupted of its normal course. |
| Ontology: | Phenotypic Quality Ontology [PATO:0001507] |