| Phenotype: | Rohon-Beard neuron voltage-gated sodium channel complex accumulation Rohon-Beard neuron endoplasmic reticulum, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | Rohon-Beard neuron |
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| Synonyms: | RB neuron, Rohon-Beard cell, Rohon-Beard neurons |
| Definition: | Primary sensory neurons with cell bodies located in the dorsal spinal cord, that innervate the integument of the trunk and tail at early larval stages. The cutaneous axons of Rohon-Beard neurons display a broad spectrum of peripheral axon branching patterns. Most Rohon-Beard neurons undergo apoptosis by 5dpf. |
| Ontology: | Anatomy Ontology [ZFA:0009150] |
| Name: | voltage-gated sodium channel complex |
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| Synonyms: | voltage gated sodium channel complex, voltage-dependent sodium channel complex, voltage-sensitive sodium channel complex |
| Definition: | A sodium channel in a cell membrane whose opening is governed by the membrane potential. |
| Ontology: | GO: Cellular Component [GO:0001518] QuickGO AmiGO |
| Name: | accumulation |
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| Synonyms: | pooled |
| Definition: | A structural quality of the collection or massing of one physical object within another physical object. |
| Ontology: | Phenotypic Quality Ontology [PATO:0002269] |
| Name: | endoplasmic reticulum |
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| Synonyms: | ER |
| Definition: | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
| Ontology: | GO: Cellular Component [GO:0005783] QuickGO AmiGO |