Phenotype: autophagosome-lysosome fusion disrupted, abnormal
Note: This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name.
Name: autophagosome-lysosome fusion
Synonyms: autophagosome-vacuole fusion
Definition: The process in which autophagosomes, double-membraned vesicles containing cytoplasmic material, fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the autophagosome.
Ontology: GO: Biological Process [GO:0061909]    QuickGO    AmiGO
Name: disrupted
Synonyms:
Definition: A quality of a single process inhering in a bearer by virtue of the bearer's being interrupted of its normal course.
Ontology: Phenotypic Quality Ontology [PATO:0001507]