| Phenotype: | pharyngeal arch transforming growth factor beta receptor signaling pathway decreased process quality, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | pharyngeal arch |
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| Synonyms: | pharyngeal arches |
| Definition: | One of a series of paired bony or cartilaginous arches that develop along the lateral walls of the foregut. The pharyngeal arches have developmental contributions from endoderm, mesoderm, and neural crest cells and are separated by anterior lateral endoderm out-pockets known as pharyngeal pouches. There are seven pharyngeal arches. |
| Ontology: | Anatomy Ontology [ZFA:0001306] |
| Name: | transforming growth factor beta receptor signaling pathway |
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| Synonyms: | TGF-beta receptor signaling pathway, TGF-beta receptor signalling pathway, TGFbeta receptor signaling pathway, TGFbeta receptor signalling pathway, transforming growth factor beta receptor signalling pathway |
| Definition: | The series of molecular signals initiated by an extracellular ligand binding to a transforming growth factor beta receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. |
| Ontology: | GO: Biological Process [GO:0007179] QuickGO AmiGO |
| Name: | decreased process quality |
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| Synonyms: | |
| Definition: | A quality of a process that has a value that is decreased compared to normal or average. |
| Ontology: | Phenotypic Quality Ontology [PATO:0002302] |