| Phenotype: | heart desmosome disorganized, abnormal |
|---|---|
| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | heart |
|---|---|
| Synonyms: | |
| Definition: | Blood pumping organ composed of four components: sinus venosus, atrium, cardiac ventricle and bulbus arteriosus. |
| Ontology: | Anatomy Ontology [ZFA:0000114] |
| Name: | desmosome |
|---|---|
| Synonyms: | macula adherens, spot desmosome |
| Definition: | A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism. |
| Ontology: | GO: Cellular Component [GO:0030057] QuickGO AmiGO |
| Name: | disorganized |
|---|---|
| Synonyms: | |
| Definition: | A structural quality inhering in a bearer by virtue of the bearer's lacking organisation. |
| Ontology: | Phenotypic Quality Ontology [PATO:0000937] |