GLI-SUFU complex

Term ID

GO:1990788

Synonyms

Definition

A protein repressing GLI's transcription factor activity when SMO signaling is inactive. Upon ligand binding to the upstream receptor PTC (Patched) GLI dissociates from SUFU and activates transcription of hedgehog-target genes. In mammals it consists of SUFU and one of the GLI family proteins. 24311597

References

Ontology

GO: Cellular Component    QuickGO    AmiGO