Search Ontology:
GO: Cellular Component
Nkx-2.5 complex
- Term ID
- GO:1990664
- Synonyms
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- Nkx-2.5 homodimer complex
- NKX.2-5 homodimer complex
- NKX2.5 complex
- NKX2E homodimer complex
- Definition
- A transcription factor complex formed by two or more subunits of Nkx-2.5. Nkx-2.5 is an evolutionary conserved transcription factor important for the specification and differentiation of cardiomyocytes during heart development. It is also required for spleen development. It binds DNA either as a monomer, or a homodimer, or a heterodimer complex to activate or inhibit expression of genes. 22849347
- References
- Ontology
- GO: Cellular Component QuickGO AmiGO
- is a type of
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Phenotype
Phenotype caused by Genes