ATF4-CREB1 transcription factor complex

Term ID

GO:1990589

Synonyms

Definition

Transcription factor complex consisting of ATF4 and CREB1 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') as part of the positive regulation of transcription. Regulatory targets include the GRP78 (HSPA5) promoter in humans, whose activation by this complex is part of the ER stress response pathway. 12871976

References

Ontology

GO: Cellular Component    QuickGO    AmiGO