CLOCK-BMAL transcription complex

Term ID

GO:1990513

Synonyms

• CLOCK/BMAL complex

Definition

Transcription factor complex which interacts with E-box regulatory elements in target genes, including Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2), to activate their transcription during the daytime. The CRY-PER complexes inhibit CLOCK-BMAL1-driven transcription in a negative feedback loop to generate circadian rhythms. 23229515

References

Ontology

GO: Cellular Component    QuickGO    AmiGO