Search Ontology:
GO: Cellular Component

Rhino-Deadlock-Cutoff Complex

Term ID
GO:1990469
Synonyms
  • RDC complex
  • rhi-del-cuff complex
Definition
Protein complex found in Drosophila consisting of the gene products of cuff, del and rhi. It regulates the licensing of transcription of dual-strand PIWI interacting RNA (piRNA) source loci by binding to dual-strand-cluster chromatin, probably via the H3K9me3-binding activity of Rhi. Rhi binding brings the putative termination cofactor Cuff in close proximity to the nascent piRNA precursor transcript which it appears to protect from degradation. 24906153
References
Ontology
GO: Cellular Component    QuickGO    AmiGO
Relationships
is part of
is a type of
Phenotype
Phenotype caused by Genes