SeqA-DNA complex

Term ID

GO:1990097

Synonyms

• SeqA-dsDNA complex
• SeqA-hemimethylated DNA complex
• SeqA-hemimethylation dsDNA complex

Definition

A protein-DNA complex that contains an oligomer of SeqA bound to GATC sites in methylated or newly-synthesized, hemi-methylated double-stranded DNA, with preference for the latter. Binding of SeqA to hemimethylated DNA sequesters oriC, prevents re-methylation of DNA by Dam and in turn stops premature re-initiation of replication during one replication cycle. (3)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO