serotonin-activated cation-selective channel complex

Term ID

GO:1904602

Synonyms

• 5-HT-3 receptor complex
• 5-HT3 receptor complex
• 5-hydroxytryptamine receptor 3 complex
• 5HT3 receptor complex
• serotonin receptor complex

Definition

A protein complex which is capable of serotonin-activated cation-selective channel activity. Mainly found in pre- and postsynaptic membranes of the brain and gastrointestinal tract. Depending on its location it transports Ca2+, Mg2+, Na+ or K+. It is always a pentamer, containing at least the 5HT3A subunit forming 5HT3A homopentamers or 5HT3A/B heteropentamers. In human, 5HT3A/C, A/D and A/E heteropentamers also exist. 16116092

References

Ontology

GO: Cellular Component    QuickGO    AmiGO