Search Ontology:
GO: Biological Process

chromosomal 5-methylcytosine DNA demethylation, oxidative deamination pathway

Term ID
GO:0141168
Synonyms
  • epigenetic 5-methylcytosine DNA demethylation, oxidative deamination pathway
  • epigenetic DNA demethylation, oxidative deamination pathway
Definition
An epigenetic cytosine DNA demethylation pathway that includes a deamination step to produce either a thymine (T), or a 5-hydroxymethyluracil (5hmU), if the 5meC had first been converted to 5hmC. A DNA glycosylase (e. g. TDG) recognizes the T mispaired with a G or the 5hmC and excises the modified base to initiate its replacement with unmethylated cytosine through base excision repair. (3)
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes