Search Ontology:
GO: Biological Process

piRNA-mediated gene silencing by mRNA destabilization

Term ID
GO:0140991
Synonyms
Definition
A cytoplasmic post-transcriptional gene silencing pathway in which piRNAs direct the cleavage of target mRNAs. The target mRNA, often transcribed from a transposable element, is destabilized by the activity of a PIWI class endonuclease within the piRNA-induced silencing complex. This may also be accompanied by mRNA deadenylation and decapping. (2)
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is a type of
has subtype
Phenotype
Phenotype caused by Genes
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