Search Ontology:
GO: Biological Process

target-directed miRNA degradation

Term ID
GO:0140958
Synonyms
  • target-directed microRNA degradation
  • TDMD
Definition
The process in which a miRNA is targeted for degradation by a non-coding RNA or mRNA. The binding of an RNA to a target miRNA within a RISC complex results in either ubiquitin-mediated degradation of AGO protein or the displacement of the 3' end of the miRNA, exposing it to nucleases. (2)
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes