Search Ontology:
GO: Molecular Function
histone H3K27 dimethyltransferase activity
- Term ID
- GO:0140952
- Synonyms
-
- histone H3-K27 dimethylase activity
- histone H3-K27 dimethylation
- histone H3K27 dimethylase activity
- histone H3K27 dimethylation
- histone H3K27 mono/dimethylase activity
- histone lysine N-dimethyltransferase activity (H3-K27 specific)
- Definition
- Catalysis of the reaction: L-lysyl27-[histone H3] + 2 S-adenosyl-L-methionine = 2 H+ + N6,N6-dimethyl-L-lysyl27-[histone H3] + 2 S-adenosyl-L-homocysteine. This reaction is the successive addition of two methyl groups to the unmethylated lysine residue at position 27 of histone H3, producing histone H3K27me2.
- References
-
- EC:2.1.1.371
- RHEA:64452
- Ontology
- GO: Molecular Function QuickGO AmiGO
- is a type of
-
Phenotype
Phenotype caused by Genes