BCOR complex

Term ID

GO:0140261

Synonyms

• BCL6 corepressor (BCOR) complex
• BCOR/BCORL1 complex
• non-canonical BCOR-PRC1.1 complex
• non-canonical PRC1-BCOR complex
• PRC1.1 complex

Definition

A protein-containing complex that monoubiquitinates histone H2A on K119, thus it facilitates the maintenance of the transcriptionally repressive state of some genes, such as BCL6. It consists of the corepressor BCOR or BCORL1, a Polycomb group (PcG) and a SCF ubiquitin ligase subcomplexes. In mammals, the core subunits of the complex include the PcG and PcG-associated proteins NSPC1, RING1, RNF2, and RYBP and the components of the SCF ubiquitin ligase, SKP1, and FBXL10. (3)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO