Search Ontology:
GO: Cellular Component

PAR polarity complex

Term ID
GO:0120157
Synonyms
  • apical polarity complex
  • BEM1-CDC24-CLA4 complex
  • Cdc42p GEF-PAK complex
  • PAR3-PAR6-atypical PKC
  • PAR3/PAR6/aPKC
  • PAR6-PAR3-aPKC complex
Definition
A protein kinase complex that is required for the establishment of a cell polarity axis during the cell division cycle. Binds directly to activated CDC42 GTPase and is required for orchestrating a cellular gradient of CDC42. In S. cerevisiae components are: BEM1, CDC24 and CLA4; from worms to vertebrates it contains a PAR6 protein, PAR3 protein and an atypical PKC. (4)
References
Ontology
GO: Cellular Component    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes
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