extrinsic apoptotic signaling pathway

Term ID

GO:0097191

Synonyms

• death receptor-mediated apoptosis
• extrinsic apoptosis
• extrinsic apoptotic pathway
• extrinsic apoptotic signaling pathway in presence of ligand
• extrinsic apoptotic signalling pathway

Definition

The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered. 17340152

References

• Reactome:R-HSA-5357769

Ontology

GO: Biological Process    QuickGO    AmiGO