Search Ontology:
GO: Biological Process
telomere maintenance via telomere trimming
- Term ID
- GO:0090737
- Synonyms
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- Definition
- A process that contributes to the maintenance of proper telomeric length and structure via the activation of telomere shortening pathways that compensate telomerase-dependent excessive telomere elongation. Telomere attrition is mediated by a mechanism which involves the generation of single-stranded C-rich telomeric DNA, and the formation and removal of double-stranded telomeric circular DNA (T-circles). Telomere trimming is an independent pathway to recombination-mediated telomere elongation and the well-documented gradual telomere attrition that accompanies cellular replication. 27918544
- References
- Ontology
- GO: Biological Process QuickGO AmiGO
- has parts
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- is a type of
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Phenotype
Phenotype caused by Genes