phospholipase C-activating angiotensin-activated signaling pathway involved in heart process

Term ID

GO:0086099

Synonyms

• angiotensin receptor signaling pathway via activation of phospholipase C involved in heart process
• cardiac angiotensin receptor signaling pathway via activation of PLC
• Gq-coupled angiotensin receptor signaling pathway involved in heart process
• phospholipase C-activating angiotensin-mediated signaling pathway involved in heart process
• PLC-activating angiotensin receptor signaling pathway involved in heart process

Definition

An angiotensin-mediated signaling pathway that contributes to a circulatory system process carried out by the heart, where the activated receptor transmits the signal via Gq-mediated activation of phospholipase C (PLC). PLC hydrolyses phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers inositol-1,4,5,-triphosphate (IP3) and diacylglycerol (DAG). DAG activates protein kinase C (PKC), whilst IP3 binds intracellular receptors to induce the release of Ca2+ from intracellular stores. 17376402

References

Ontology

GO: Biological Process    QuickGO    AmiGO