T-helper 17 cell lineage commitment

Term ID

GO:0072540

Synonyms

T-helper 17 cell fate commitment
Th17 cell lineage commitment
Th17 fate commitment

Definition

The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 17 cell, a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17.

References

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

is part of: T-helper 17 cell differentiation

T-helper 17 cell differentiation Show first 5 Terms
is a type of: T-helper cell lineage commitment

T-helper cell lineage commitment Show first 5 Terms
negatively regulated by: negative regulation of T-helper 17 cell lineage commitment

negative regulation of T-helper 17 cell lineage commitment Show first 5 Terms
positively regulated by: positive regulation of T-helper 17 cell lineage commitment

positive regulation of T-helper 17 cell lineage commitment Show first 5 Terms
regulated by: regulation of T-helper 17 cell lineage commitment

regulation of T-helper 17 cell lineage commitment Show first 5 Terms

Phenotype

Phenotype caused by Genes