N-terminal protein N-methyltransferase activity

Term ID

GO:0071885

Synonyms

• X-Pro-Lys N-terminal methyltransferase

Definition

Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the alpha-amino group of the N-terminal amino or imino acid residue of a protein substrate. For example, yeast Tae1p and mammalian family member METTL11A preferentially modify the N-terminal residue of substrates with the N-terminal sequence X-Pro-Lys, where X can be Pro, Ala, or Ser. 20481588

References

• EC:2.1.1.244

Ontology

GO: Molecular Function    QuickGO    AmiGO