pheromone response MAPK cascade

Term ID

GO:0071507

Synonyms

• conjugation with cellular fusion, MAPKKK cascade
• Fus3 signaling cascade
• MAPK cascade involved in conjugation with cellular fusion
• MAPK signaling in response to pheromone
• MAPKKK cascade involved in conjugation with cellular fusion
• MAPKKK cascade involved in mating response
• pheromone MAPK module

Definition

A MAPK cascade containing at least the Fus3 MAP kinase. It starts with the activation of Ste20, a MAP4K, which activates Ste11, a MAP3K, which in turn activate Ste7, a MAP2K, which activates Fus3. The kinases in each tier phosphorylate and activate the kinases in the downstream tier. This MAPK cascade is triggered by a pheromone activating its G protein-coupled receptor, and results in cellular responses that lead to conjugation with cellular fusion. 17604854

References

Ontology

GO: Biological Process    QuickGO    AmiGO