U2-type catalytic step 2 spliceosome

Term ID

GO:0071007

Synonyms

• GT-AG catalytic step 2 spliceosome
• major catalytic step 2 spliceosome
• mammalian U2-type spliceosomal complex C
• mammalian U2-type spliceosomal complex C1
• yeast U2-type spliceosomal complex A2-2

Definition

A spliceosomal complex that contains the U2, U5 and U6 snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U2, U5 and U6 snRNPs. (4)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO