nuclear pore transmembrane ring

Term ID

GO:0070762

Synonyms

• NDC1 complex
• NDC1 subcomplex

Definition

A subcomplex of the nuclear pore complex (NPC) that spans the nuclear membrane and anchors the NPC to the nuclear envelope. In S. cerevisiae, the transmembrane ring is composed of Pom152p, Pom34p, and Ndc1p. In vertebrates, it is composed of Gp210, Ndc1, and Pom121. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometime referred to as the Ndc1 complex. (4)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO