death domain binding

Term ID

GO:0070513

Synonyms

Definition

Binding to a death domain of a protein. The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. DD bind each other forming oligomers. Some DD-containing proteins are involved in the regulation of apoptosis and inflammation through their activation of caspases and NF-kappaB. (2)

References

Ontology

GO: Molecular Function    QuickGO    AmiGO