Search Ontology:
GO: Biological Process
R-loop processing
- Term ID
- GO:0062176
- Synonyms
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- R-loop disassembly
- Definition
- A DNA metabolic process that results in the disassembly of R-loops. R-loops are three-stranded nucleic acid structures consisitng of an RNA:DNA heteroduplex and a looped-out non-template strand. Aberrant formation and persistence of R-loops block transcription elongation and cause DNA damage. Mechanisms that resolve R-loops are essential for genome stability. (3)
- References
- Ontology
- GO: Biological Process QuickGO AmiGO
- is a type of
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Phenotype
Phenotype caused by Genes