NAD+ nucleotidase, cyclic ADP-ribose generating

Term ID

GO:0061809

Synonyms

• ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
• NAD hydrolase
• NAD(+) nucleosidase
• NADase
• nicotinamide adenine dinucleotide nucleosidase

Definition

Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose, in a two steps reaction: first an ADP-ribosyl cyclase reaction, followed by a cyclic ADP-ribose hydrolase reaction. 11866528

References

• EC:3.2.2.6
• MetaCyc:NADNUCLEOSID-RXN
• Reactome:R-HSA-8870346
• Reactome:R-HSA-8938076
• Reactome:R-HSA-9637699

Ontology

GO: Molecular Function    QuickGO    AmiGO