Tapasin-ERp57 complex

Term ID

GO:0061779

Synonyms

Definition

Subunit of the MHC class I peptide loading complex (GO:0042824) (=PLC) involved in the assembly of the heavy-chain-beta2-microglobulin dimers of the MHC class I molecules that fold with eight to ten residue peptides in the endoplasmic reticulum. Required for the inhibition of the reduction of the disulfide bonds of the heavy chains and the assembly and stabilization of the PLC, suggesting it may play a structural rather than a catalytic role. 17603487

References

Ontology

GO: Cellular Component    QuickGO    AmiGO