Search Ontology:
GO: Molecular Function

large conductance calcium-activated potassium channel activity

Term ID
GO:0060072
Synonyms
  • BK calcium-activated potassium channel activity
  • BK channel activity
  • BK KCa channel activity
  • large conductance KCa channel activity
Definition
Enables the transmembrane transfer of potassium by a channel with a unit conductance of 100 to 220 picoSiemens that opens in response to stimulus by concerted actions of internal calcium ions and membrane potential. Large conductance calcium-activated potassium channels are less sensitive to calcium than are small or intermediate conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. (2)
References
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
is a type of
negatively regulated by
positively regulated by
regulated by
Phenotype
Phenotype caused by Genes