Search Ontology:
GO: Molecular Function
large conductance calcium-activated potassium channel activity
- Term ID
- GO:0060072
- Synonyms
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- BK calcium-activated potassium channel activity
- BK channel activity
- BK KCa channel activity
- large conductance KCa channel activity
- Definition
- Enables the transmembrane transfer of potassium by a channel with a unit conductance of 100 to 220 picoSiemens that opens in response to stimulus by concerted actions of internal calcium ions and membrane potential. Large conductance calcium-activated potassium channels are less sensitive to calcium than are small or intermediate conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. (2)
- References
- Ontology
- GO: Molecular Function QuickGO AmiGO
- is a type of
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- negatively regulated by
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- positively regulated by
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- regulated by
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Phenotype
Phenotype caused by Genes