L-histidine N(alpha)-methyltransferase activity

Term ID

GO:0052706

Synonyms

• histidine methyltransferase activity
• histidine N-methyltransferase activity
• S-adenosyl-L-methionine:L-histidine alpha-N-methyltransferase activity
• S-adenosyl-L-methionine:L-histidine Nalpha-methyltransferase activity

Definition

Catalysis of the reaction: L-histidine + 3 S-adenosyl-L-methionine <=> 3 H(+) + hercynine + 3 S-adenosyl-L-homocysteine. This reaction is the addition of three methyl groups to L-histidine to form N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine).

References

• EC:2.1.1.44
• KEGG_REACTION:R01169
• MetaCyc:RXN-14431
• RHEA:38471

Ontology

GO: Molecular Function    QuickGO    AmiGO