Search Ontology:
GO: Molecular Function

G-quadruplex DNA binding

Term ID
GO:0051880
Synonyms
  • G quadruplex DNA binding
  • G quartet binding
  • G quartet DNA binding
  • G-DNA binding
  • G-quartet binding
  • G-quartet DNA binding
  • quadruplex DNA binding
  • tetraplex DNA binding
Definition
Binding to G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome. (2)
References
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
is a type of
has subtype
negatively regulated by
positively regulated by
regulated by
Phenotype
Phenotype caused by Genes