BH domain binding

Term ID

GO:0051400

Synonyms

Bcl-2 homology domain binding

Definition

Binding to a Bcl-2 homology (BH) protein domain. Bcl-2-related proteins share homology in one to four conserved regions designated the Bcl-2 homology (BH) domains BH1, BH2, BH3 and BH4. These domains contribute at multiple levels to the function of these proteins in cell death and survival. Anti-apoptotic members of the Bcl-2 family have four BH domains (BH1-BH4). Pro-apoptotic members have fewer BH domains. (4)

References

Ontology

GO: Molecular Function QuickGO AmiGO

Relationships

is a type of: protein domain specific binding

protein domain specific binding Show first 5 Terms
has subtype: BH1 domain binding BH2 domain binding BH3 domain binding BH4 domain binding

BH1 domain binding BH2 domain binding BH3 domain binding BH4 domain binding Show first 5 Terms

Phenotype

Phenotype caused by Genes