Search Ontology:
GO: Biological Process

leukocyte tethering or rolling

Term ID
GO:0050901
Synonyms
Definition
Transient adhesive interactions between leukocytes and endothelial cells lining blood vessels. Carbohydrates on circulating leukocytes bind selectins on the vessel wall causing the leukocytes to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between selectins and their ligands. Typically the first step in cellular extravasation (the movement of leukocytes out of the circulatory system, towards the site of tissue damage or infection). (6)
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is part of
is a type of
negatively regulated by
positively regulated by
regulated by
Phenotype
Phenotype caused by Genes