lovastatin nonaketide synthase activity

Term ID

GO:0050637

Synonyms

• acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing, thioester-hydrolysing)

Definition

Catalysis of the reaction: S-adenosyl-L-methionine(1+) + acetyl-CoA + 18 H+ + 8 malonyl-CoA + 11 NADPH = S-adenosyl-L-homocysteine + 8 CO2 + 9 CoA + dihydromonacolin L + 6 H2O + 11 NADP+. 2.3.1.161

References

• EC:2.3.1.161
• KEGG_REACTION:R07251
• MetaCyc:2.3.1.161-RXN
• RHEA:18565

Ontology

GO: Molecular Function    QuickGO    AmiGO