Search Ontology:
GO: Molecular Function

cholate-CoA ligase activity

Term ID
GO:0047747
Synonyms
  • 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate--CoA ligase activity
  • 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate-CoA ligase activity
  • 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate:CoA ligase (AMP-forming) activity
  • 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoate-CoA ligase activity
  • 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoate-CoA synthetase activity
  • 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl coenzyme A synthetase activity
  • 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate-CoA ligase activity
  • 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate:CoA ligase (AMP-forming)
  • 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate-CoA ligase activity
  • 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate-CoA synthetase activity
  • 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl coenzyme A synthetase activity
  • BAL activity
  • bile acid CoA ligase activity
  • bile acid coenzyme A ligase activity
  • cholate thiokinase activity
  • cholate:CoA ligase (AMP-forming)
  • cholic acid:CoA ligase activity
  • cholic thiokinase activity
  • choloyl coenzyme A synthetase activity
  • choloyl-CoA synthetase activity
  • cholyl-CoA synthetase activity
  • THCA-CoA ligase activity
  • trihydroxycoprostanoyl-CoA synthetase activity
Definition
Catalysis of the reactions: (1) ATP + cholate + CoA = AMP + diphosphate + choloyl-CoA and (2) ATP + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + CoA = AMP + diphosphate + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA. This reaction is the first step in the conjugation of bile acids with amino acids, converting bile acids into their acyl-CoA thioesters. Chenodeoxycholate, deoxycholate, lithocholate and trihydroxycoprostanoate can also act as substrates. 6.2.1.7
References
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes