15-hydroxyprostaglandin-I dehydrogenase (NADP+) activity

Term ID

GO:0047033

Synonyms

• (5Z,13E)-(15S)-6,9alpha-epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate:NADP+ 15-oxidoreductase activity
• NADP+-dependent PGI2-specific 15-hydroxyprostaglandin dehydrogenase activity
• NADP-linked 15-hydroxyprostaglandin (prostacyclin) dehydrogenase activity
• PG I2 dehydrogenase activity
• prostacyclin dehydrogenase activity

Definition

Catalysis of the reaction: NADP+ + prostaglandin I(2) = 15-dehydro-prostaglandin I(2) + H+ + NADPH. 1.1.1.231

References

• EC:1.1.1.231
• KEGG_REACTION:R03520
• MetaCyc:1.1.1.231-RXN
• RHEA:21420

Ontology

GO: Molecular Function    QuickGO    AmiGO