histone H4K16 deacetylase activity, NAD-dependent

Term ID

GO:0046970

Synonyms

• NAD-dependent histone deacetylase activity (H4-K16 specific)
• NAD-dependent histone H4-K16 deacetylase activity
• NAD-dependent histone H4K16 deacetylase activity

Definition

Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + NAD+ + H2O = histone H4 L-lysine (position 16) + 2''-O-acetyl-ADP-D-ribose + nicotinamide. This reaction transfers an acetyl group attached to a lysine residue in H4K16 to NAD, producing nicotinamide. 28450737

References

Ontology

GO: Molecular Function    QuickGO    AmiGO