Search Ontology:
GO: Molecular Function

1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Term ID
GO:0046934
Synonyms
  • phosphatidylinositol 3-kinase activity, class I
  • phosphatidylinositol 3-kinase activity, class II
  • phosphatidylinositol 3-kinase, class I, catalyst activity
  • phosphatidylinositol-4,5-bisphosphate 3-kinase activity
  • type I phosphoinositide 3-kinase activity
Definition
Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + H+. 2.7.1.153
References
  • EC:2.7.1.153
  • KEGG_REACTION:R04545
  • MetaCyc:2.7.1.153-RXN
  • RHEA:21292
  • Reactome:R-HSA-1226014
  • Reactome:R-HSA-1250370
  • Reactome:R-HSA-1250462
  • Reactome:R-HSA-1306957
  • Reactome:R-HSA-1306979
  • Reactome:R-HSA-1676048
  • Reactome:R-HSA-177939
  • Reactome:R-HSA-1839091
  • Reactome:R-HSA-1839107
  • Reactome:R-HSA-186800
  • Reactome:R-HSA-198266
  • Reactome:R-HSA-201510
  • Reactome:R-HSA-202365
  • Reactome:R-HSA-2029271
  • Reactome:R-HSA-2076220
  • Reactome:R-HSA-2316434
  • Reactome:R-HSA-2394007
  • Reactome:R-HSA-2424480
  • Reactome:R-HSA-2730870
  • Reactome:R-HSA-389158
  • Reactome:R-HSA-392300
  • Reactome:R-HSA-437162
  • Reactome:R-HSA-5218819
  • Reactome:R-HSA-5637801
  • Reactome:R-HSA-5654690
  • Reactome:R-HSA-5654692
  • Reactome:R-HSA-5654697
  • Reactome:R-HSA-5654701
  • Reactome:R-HSA-5654705
  • Reactome:R-HSA-5654709
  • Reactome:R-HSA-5654714
  • Reactome:R-HSA-5654717
  • Reactome:R-HSA-5655235
  • Reactome:R-HSA-5655289
  • Reactome:R-HSA-5655290
  • Reactome:R-HSA-5655323
  • Reactome:R-HSA-8852019
  • Reactome:R-HSA-9021627
  • Reactome:R-HSA-9028519
  • Reactome:R-HSA-9603445
  • Reactome:R-HSA-9664664
  • Reactome:R-HSA-9664940
  • Reactome:R-HSA-9665407
  • Reactome:R-HSA-9672162
  • Reactome:R-HSA-9672177
  • Reactome:R-HSA-9712084
  • Reactome:R-HSA-9860816
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes