negative regulation of mitotic metaphase/anaphase transition

Term ID

GO:0045841

Synonyms

down regulation of mitotic metaphase/anaphase transition
down-regulation of mitotic metaphase/anaphase transition
downregulation of mitotic metaphase/anaphase transition
inhibition of mitotic metaphase/anaphase transition

Definition

Any process that stops, prevents, or reduces the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.

References

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

is a type of: biological regulation negative regulation of metaphase/anaphase transition of cell cycle negative regulation of mitotic cell cycle phase transition negative regulation of mitotic nuclear division negative regulation of mitotic sister chromatid separation ... Show All 6 Terms

biological regulation negative regulation of metaphase/anaphase transition of cell cycle negative regulation of mitotic cell cycle phase transition negative regulation of mitotic nuclear division negative regulation of mitotic sister chromatid separation regulation of mitotic metaphase/anaphase transition Show first 5 Terms
has subtype: mitotic spindle assembly checkpoint signaling

mitotic spindle assembly checkpoint signaling Show first 5 Terms
negatively regulates: metaphase/anaphase transition of mitotic cell cycle

metaphase/anaphase transition of mitotic cell cycle Show first 5 Terms

Phenotype

Phenotype caused by Genes