protein insertion into ER membrane

Term ID

GO:0045048

Synonyms

integral ER membrane protein localization
integral ER membrane protein positioning
localization of protein in ER membrane
positioning of protein in ER membrane
protein insertion into endoplasmic reticulum membrane
protein-endoplasmic reticulum insertion
protein-ER insertion

Definition

The process that results in incorporation of a protein into an endoplasmic reticulum (ER) membrane. It depends on specific topogenic sequences of amino acids that ensure that a protein acquires the proper orientation during its insertion into the ER membrane. 0716731363

References

Reactome:R-HSA-9609523

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

is part of: endoplasmic reticulum organization protein localization to organelle

endoplasmic reticulum organization protein localization to organelle Show first 5 Terms
is a type of: protein insertion into membrane

protein insertion into membrane Show first 5 Terms
has subtype: multi-pass transmembrane protein insertion into ER membrane protein insertion into ER membrane by internal uncleaved signal-anchor sequence protein insertion into ER membrane by N-terminal cleaved signal sequence protein insertion into ER membrane by stop-transfer membrane-anchor sequence tail-anchored membrane protein insertion into ER membrane

multi-pass transmembrane protein insertion into ER membrane protein insertion into ER membrane by internal uncleaved signal-anchor sequence protein insertion into ER membrane by N-terminal cleaved signal sequence protein insertion into ER membrane by stop-transfer membrane-anchor sequence tail-anchored membrane protein insertion into ER membrane Show first 5 Terms

Phenotype

Phenotype caused by Genes