protein targeting to ER

Term ID

GO:0045047

Synonyms

• protein targeting to endoplasmic reticulum
• protein-endoplasmic reticulum targeting
• protein-ER targeting

Definition

The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane. 0716731363

References

Ontology

GO: Biological Process    QuickGO    AmiGO