negative regulation of gene expression via chromosomal CpG island methylation

Term ID

GO:0044027

Synonyms

• DNA hypermethylation of CG island
• DNA hypermethylation of CpG island
• epigenetic regulation of gene expression via CpG island hypermethylation
• hypermethylation of CpG island
• negative regulation of gene expression via chromosomal CG dinucleotide methylation
• negative regulation of gene expression via chromosomal CpG dinucleotide methylation
• negative regulation of gene expression via chromosomal DNA cytosine methylation
• negative regulation of gene expression via CpG island hypermethylation
• negative regulation of gene expression via CpG island methylation

Definition

An epigenetic gene regulation mechanism that negatively regulates gene expression by methylation of cytosine residues in chromosomal CpG islands. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide associated with the transcription start site of genes. (2)

References

Ontology

GO: Biological Process    QuickGO    AmiGO