Search Ontology:
GO: Biological Process

negative regulation of gene expression via chromosomal CpG island methylation

Term ID
GO:0044027
Synonyms
  • DNA hypermethylation of CG island
  • DNA hypermethylation of CpG island
  • epigenetic regulation of gene expression via CpG island hypermethylation
  • hypermethylation of CpG island
  • negative regulation of gene expression via chromosomal CG dinucleotide methylation
  • negative regulation of gene expression via chromosomal CpG dinucleotide methylation
  • negative regulation of gene expression via chromosomal DNA cytosine methylation
  • negative regulation of gene expression via CpG island hypermethylation
  • negative regulation of gene expression via CpG island methylation
Definition
An epigenetic gene regulation mechanism that negatively regulates gene expression by methylation of cytosine residues in chromosomal CpG islands. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide associated with the transcription start site of genes. (2)
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes