Search Ontology:
GO: Molecular Function

insulin receptor substrate binding

Term ID
GO:0043560
Synonyms
  • insulin receptor substrate [protein] binding
  • IRS [protein] binding
  • IRS binding
Definition
Binding to an insulin receptor substrate (IRS) protein, an adaptor protein that bind to the transphosphorylated insulin and insulin-like growth factor receptors, are themselves phosphorylated and in turn recruit SH2 domain-containing signaling molecules to form a productive signaling complex. 12829233
References
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes