insulin receptor substrate binding

Term ID

GO:0043560

Synonyms

• insulin receptor substrate [protein] binding
• IRS [protein] binding
• IRS binding

Definition

Binding to an insulin receptor substrate (IRS) protein, an adaptor protein that bind to the transphosphorylated insulin and insulin-like growth factor receptors, are themselves phosphorylated and in turn recruit SH2 domain-containing signaling molecules to form a productive signaling complex. 12829233

References

Ontology

GO: Molecular Function    QuickGO    AmiGO