amyloid precursor protein catabolic process

Term ID

GO:0042987

Synonyms

amyloid precursor protein breakdown
amyloid precursor protein catabolism
amyloid precursor protein degradation
APP catabolic process
APP catabolism

Definition

The chemical reactions and pathways resulting in the breakdown of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease.

References

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

has parts: aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process metalloendopeptidase activity involved in amyloid precursor protein catabolic process

aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process metalloendopeptidase activity involved in amyloid precursor protein catabolic process Show first 5 Terms
is a type of: amyloid precursor protein metabolic process

amyloid precursor protein metabolic process Show first 5 Terms
has subtype: amyloid-beta formation

amyloid-beta formation Show first 5 Terms
negatively regulated by: negative regulation of amyloid precursor protein catabolic process

negative regulation of amyloid precursor protein catabolic process Show first 5 Terms
positively regulated by: positive regulation of amyloid precursor protein catabolic process

positive regulation of amyloid precursor protein catabolic process Show first 5 Terms
regulated by: regulation of amyloid precursor protein catabolic process

regulation of amyloid precursor protein catabolic process Show first 5 Terms

Phenotype

Phenotype caused by Genes