symbiont-mediated arrest of host cell cycle during G2/M transition

Term ID

GO:0039592

Synonyms

• host G2/M cell cycle arrest by virus
• perturbation by virus of G2/M transition of host mitotic cell cycle
• suppression by virus of G2/M transition of host mitotic cell cycle

Definition

A process in which a symbiont interferes with the progression of the host mitotic cell cycle from G2 phase to M phase, leading to arrest in G2 phase. The arrest in G2/M allows some viruses to replicate their genome before cells enter mitosis. Alternatively, it can inhibit the antiviral immune response by preventing the clonal expansion of infected lymphocytes. (3)

References

• VZ:876

Ontology

GO: Biological Process    QuickGO    AmiGO