Search Ontology:
GO: Biological Process

symbiont-mediated suppression of host JAK-STAT cascade via inhibition of host TYK2 activity

Term ID
GO:0039574
Synonyms
  • disruption by virus of host JAK-STAT cascade via inhibition of host TYK2 activity
  • suppression by virus of host JAK-STAT cascade via inhibition of host TYK2 activity
  • suppression by virus of host non-receptor tyrosine-protein kinase TYK2 activity
  • suppression by virus of host TYK2 activity
Definition
A process in which a symbiont interferes with, inhibits or disrupt a JAK-STAT signal cascade in the host organism by reducing the activity of host TYK2 (tyrosine kinase 2). TYK2 is an intracellular signal-transducing tyrosine kinase involved in numerous cytokines and interferons signaling pathways and transmits the cytokine signal by phosphorylating receptor subunits. (2)
References
  • VZ:720
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes