Search Ontology:
GO: Biological Process
symbiont-mediated suppression of host JAK-STAT cascade via inhibition of host TYK2 activity
- Term ID
- GO:0039574
- Synonyms
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- disruption by virus of host JAK-STAT cascade via inhibition of host TYK2 activity
- suppression by virus of host JAK-STAT cascade via inhibition of host TYK2 activity
- suppression by virus of host non-receptor tyrosine-protein kinase TYK2 activity
- suppression by virus of host TYK2 activity
- Definition
- A process in which a symbiont interferes with, inhibits or disrupt a JAK-STAT signal cascade in the host organism by reducing the activity of host TYK2 (tyrosine kinase 2). TYK2 is an intracellular signal-transducing tyrosine kinase involved in numerous cytokines and interferons signaling pathways and transmits the cytokine signal by phosphorylating receptor subunits. (2)
- References
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- VZ:720
- Ontology
- GO: Biological Process QuickGO AmiGO
- is a type of
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Phenotype
Phenotype caused by Genes