symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity

Term ID

GO:0039545

Synonyms

• inhibition of host MAVS by virus
• suppression by virus of host MAVS activity
• suppression by virus of host mitochondrial antiviral-signaling protein
• suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity

Definition

A process in which a symbiont interferes with, inhibits or disrupts a cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host MAVS (mitochondrial antiviral signaling protein). MAVS is a signal transducer that lies downstream of the viral RNA receptors MDA-5 and RIG-I to coordinate host innate immune responses. (2)

References

• VZ:704

Ontology

GO: Biological Process    QuickGO    AmiGO