Search Ontology:
GO: Biological Process
granulocyte-macrophage colony-stimulating factor signaling pathway
- Term ID
- GO:0038157
- Synonyms
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- CSF2 signaling pathway
- GM-CSF receptor signaling pathway
- GM-CSF signaling pathway
- granulocyte-macrophage colony-stimulating factor receptor signaling pathway
- granulocyte-macrophage colony-stimulating factor signalling pathway
- Definition
- The series of molecular signals initiated by the binding of the cytokine granulocyte macrophage colony-stimulating factor (GM-CSF) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. GM-CSF binds to a heterodimer receptor (CSF2R) consisting of an alpha ligand-binding subunit, and a common beta subunit that is shared with other cytokine receptors. 17027509
- References
- Ontology
- GO: Biological Process QuickGO AmiGO
- has parts
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- is a type of
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Phenotype
Phenotype caused by Genes